Brandeis University

Coherent Spatial Coding Mediated By Theta Oscillations

Zielinski MC*, Shin JD*, Jadhav SP (2019), “Coherent coding of spatial position mediated by theta oscillations in the hippocampus and prefrontal cortex”, Journal of Neuroscience, 39(23), 4550-4565.
  This study established that theta oscillations mediate a temporal coordination mechanism for coherent coding of spatial position in hippocampal-prefrontal networks during memory-guided behavior. We found that ensemble activity in the prefrontal cortex encodes animal’s current position coherently with hippocampal populations at a theta-cycle timescale, and theta-phase associated spiking refines this spatial coding in both regions.

Also, see a related review:
Zielinski MC*, Tang W*, Jadhav SP (2020), “The role of replay and theta sequences in mediating hippocampal-prefrontal interactions for memory and cognition”, Hippocampus, 30(1):60-72.