Brandeis University

Refinement And Reactivation Of A Taste-Responsive Hippocampal Network

Herzog LE, Katz DB, Jadhav SP (2020), “Refinement and reactivation of a taste-responsive hippocampal network”, Current Biology, 30, 1306-1311.
  This study followed up on the discovery of a taste responsive hippocampal sub-network to examine changes in this network during novel taste experience. Our results showed that taste responsiveness is associated with initially larger spatially responsive place fields which are selectively refined with experience. This refinement or reorganization is supported by selective reactivation during sharp-wave ripples (SWRs). This phenomenon can thus underlie a mechanism to signal areas of food availability with experience.